A Bi-directional Electrochemically Driven Micro Liquid Dosing System with Integrated Sensowactuator Electrodes

نویسندگان

  • Sebastian Bohm
  • Wouter Olthuis
  • Piet Bergveld
چکیده

In this contribution a micro liquid dosing system is presented, which allows bi-directional manipulation of fluids (i.e. pushing out and pulling in of liquids) by the electrochemical generation and removal of gas bubbles. Bi-directionality is obtained by reversal of the actuation current thereby causing the earlier produced gasses to react back to water. This reduction of gas volume actively pulls liquid back into the system. The electrochemical actuator electrodes have been specially designed to perform the simultaneous measurement of conductivity, via which the total amount of gas can be estimated. As this amount equals the total dosed volume of liquid, dispensed volumes can be determined on-line during experiments.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Novel multisensor platforms for biomedical analysis of electrolytes and monitoring of ion-transport through biological membranes

Multielectrode sensor arrays and bi-sensor systems designed for short and/or real-time concentration measurements of sodium, potassium, chloride, bicarbonate and pH are presented. The systems used for routine measurements in a small volume of blood and in biological liquids bathing a living human bronchial epithelial cell monolayer to characterize ion-fluxes are in focus [1, 2]. Several applica...

متن کامل

Modified Bi-directional AC/DC Power Converter with Power Factor Correction

Most existing power  converters and industrial motor drive systems draw non-sinusoidal currents from the supply. Non-sinusoidal currents contained harm harmonics disturb the power supply which it causes serious concern for reliability. Other equipments that use the same power supply are adversely affected. This paper suggests the operation and performance of a new modified AC/DC converter that ...

متن کامل

Biosensor microprobes with integrated microfluidic channels for bi-directional neurochemical interaction.

This paper reports on silicon-based microprobes, 8 mm long and 250 µm × 250 µm cross-section, comprising four recessed biosensor microelectrodes (50 µm × 150 µm) per probe shank coated with an enzymatic layer for the selective detection of choline at multiple sites in brain tissue. Integrated in the same probe shank are up to two microfluidic channels for controlled local liquid delivery at a d...

متن کامل

A robust, electrochemically driven microwell drug delivery system for controlled vasopressin release.

Micro-electro-mechanical-system (MEMS) based implantable drug delivery devices represent a promising approach to achieving more precise dosing, faster release and better localization of therapeutic compounds than is possible with existing technology. Despite recent advancements, there remain challenges in being able to build systems that enable active control over the dose rate and release time...

متن کامل

iGC2: an architecture for micro gas chromatographs utilizing integrated bi-directional pumps and multi-stage preconcentrators

This paper reports an integrated micro gas chromatography (μGC) architecture which utilizes a bi-directional micropump. Four integral components—the bi-directional Knudsen pump (KP2), a two-stage preconcentrator-focuser (PCF2), a separation column, and a gas detector—are integrated in a 4.3 cm3 stack, forming a serial flow path. All four components are fabricated using the same three-mask proce...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2004